6EA5
Structure of BDBV GPcl in complex with the pan-ebolavirus mAb ADI-15878
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Envelope glycoprotein | polymer | 162 | 17768.1 | 3 | UniProt (B8XCN0) Pfam (PF01611) | Bundibugyo ebolavirus | Spike glycoprotein |
| 2 | B, D, F (B, D, F) | Glycoprotein | polymer | 111 | 12430.2 | 3 | UniProt (R4QRC0) Pfam (PF22307) UniProt (by SIFTS) (B8XCN0) | Bundibugyo ebolavirus | |
| 3 | G, I, K (H, M, Q) | ADI-15878 Fab Heavy Chain | polymer | 233 | 24743.6 | 3 | Homo sapiens (Human) | ||
| 4 | H, J, L (L, N, R) | ADI-15878 Fab Light Chain | polymer | 213 | 23093.5 | 3 | Homo sapiens (Human) | ||
| 5 | M (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1114.0 | 1 | In PDB GlyTouCan (G61751GZ) | |||
| 6 | N (I) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 7 | O, P (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A, C, E: 33 - 194 (UniProt: B8XCN0)
| PDB | External Database | Details |
|---|---|---|
| Ala 64 | Lys 64 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 234106.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2024.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 236573.3 |
