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6EA5

Structure of BDBV GPcl in complex with the pan-ebolavirus mAb ADI-15878

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, EEnvelope glycoproteinpolymer16217768.13UniProt (B8XCN0)
Pfam (PF01611)
In PDB
Bundibugyo ebolavirusSpike glycoprotein
2B, D, FGlycoproteinpolymer11112430.23UniProt (R4QRC0)
UniProt (by SIFTS) (B8XCN0)
In PDB
Bundibugyo ebolavirus
3H, M, QADI-15878 Fab Heavy Chainpolymer23324743.63Homo sapiens (Human)
4L, N, RADI-15878 Fab Light Chainpolymer21323093.53Homo sapiens (Human)
5G2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched1114.01In PDB
GlyTouCan (G61751GZ)
6Ialpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G22768VO)
7A, B2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
Sequence modifications
A, C, E: 33 - 194 (UniProt: B8XCN0)
PDBExternal DatabaseDetails
Ala 64Lys 64conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight234106.1
BranchedNumber of molecules2
Total formula weight2024.8
Non-Polymers*Number of molecules2
Total formula weight442.4
All*Total formula weight236573.3
*Water molecules are not included.

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PDB entries from 2024-04-24

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