6E54

Crystal structure of LpxC from Pseudomonas aeruginosa in complex with ligand PT802

Summary for 6E54

• Entry DOI: 10.2210/pdb6e54/pdb
• Related: 5UPG 5VWM 6C9C 6CAX 6DUI
• Descriptor: UDP-3-O-acyl-N-acetylglucosamine deacetylase, (2S)-4-{4-[4-(benzyloxy)-2-fluorophenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2R)-4-{4-[4-(benzyloxy)-2-fluorophenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, ... (7 entities in total)
• Functional Keywords: inhibitor, structural genomics, seattle structural genomics center for infectious disease, ssgcid, lpxc, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 1
• Total formula weight: 34755.65

Authors

Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-07-19, release date: 2019-06-26, Last modification date: 2023-10-11)

• Primary citation: Delker, S.L.,Mayclin, S.J.,Phan, J.N.,Abendroth, J.,Lorimer, D.,Edwards, T.E.; Crystal structure of LpxC from Pseudomonas aeruginosa in complex with ligand PT802; to be published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)