6DUI

Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT801

Summary for 6DUI

• Entry DOI: 10.2210/pdb6dui/pdb
• Related: 5UPG 5VWM 6C9C 6CAX
• Descriptor: UDP-3-O-acyl-N-acetylglucosamine deacetylase, (2R)-4-{4-[4-(benzyloxy)phenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2S)-4-{4-[4-(benzyloxy)phenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, ... (7 entities in total)
• Functional Keywords: ssgcid, lpxc, lipid a biosynthesis, structural genomics, seattle structural genomics center for infectious disease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Pseudomonas aeruginosa (strain LESB58)
• Total number of polymer chains: 1
• Total formula weight: 34728.20

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-06-20, release date: 2019-06-26, Last modification date: 2023-10-11)

• Primary citation: Phan, J.N.,Delker, S.L.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT801; to be published,

Experimental method

X-RAY DIFFRACTION (1.55 Å)