6DUI
Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT801
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 304 | 33562.1 | 1 | UniProt (B7UZI4) Pfam (PF03331) | Pseudomonas aeruginosa (strain LESB58) | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | B (A) | (2R)-4-{4-[4-(benzyloxy)phenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide | non-polymer | 470.5 | 1 | Chemie (HAY) | |||
| 3 | C (A) | (2S)-4-{4-[4-(benzyloxy)phenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide | non-polymer | 470.5 | 1 | Chemie (J1M) | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | H (A) | water | water | 18.0 | 411 | Chemie (HOH) |
Sequence modifications
A: 1 - 303 (UniProt: B7UZI4)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33562.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1166.1 | |
| All* | Total formula weight | 34728.2 |
