6E54
Crystal structure of LpxC from Pseudomonas aeruginosa in complex with ligand PT802
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 304 | 33562.1 | 1 | UniProt (P47205) Pfam (PF03331) In PDB | Pseudomonas aeruginosa | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | A | (2S)-4-{4-[4-(benzyloxy)-2-fluorophenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide | non-polymer | 488.5 | 1 | Chemie (HUM) | |||
| 3 | A | (2R)-4-{4-[4-(benzyloxy)-2-fluorophenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide | non-polymer | 488.5 | 1 | Chemie (JCG) | |||
| 4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 7 | water | water | 18.0 | 390 | Chemie (HOH) |
Sequence modifications
A: 1 - 303 (UniProt: P47205)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33562.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1193.5 | |
| All* | Total formula weight | 34755.7 |
