5UPG

Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PF-5081090

Summary for 5UPG

• Entry DOI: 10.2210/pdb5upg/pdb
• Descriptor: UDP-3-O-acyl-N-acetylglucosamine deacetylase, (2R)-4-[4-(2-fluoro-4-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, ZINC ION, ... (6 entities in total)
• Functional Keywords: ssgcid, lpxc, udp-3-o-acyl-n-acetylglucosamine deacetylase, pf-5081090, lipid a biosynthesis, structural genomics, seattle structural genomics center for infectious disease, hydrolase
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• Total number of polymer chains: 1
• Total formula weight: 34925.67

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2017-02-02, release date: 2017-03-29, Last modification date: 2023-10-04)

• Primary citation: Phan, J.N.,Delker, S.L.,Lorimer, D.D.,Edwards, T.E.; Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PF-5081090; to be published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)