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6CAX

Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT805

Summary for 6CAX
Entry DOI10.2210/pdb6cax/pdb
Related5UPG
DescriptorUDP-3-O-acyl-N-acetylglucosamine deacetylase, (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-{2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}butanamide, ZINC ION, ... (6 entities in total)
Functional Keywordsssgcid, lpxc, lipid a biosynthesis, structural genomics, seattle structural genomics center for infectious disease, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourcePseudomonas aeruginosa
Total number of polymer chains1
Total formula weight35646.48
Authors
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-02-01, release date: 2019-02-13, Last modification date: 2023-10-04)
Primary citationPhan, J.N.,Delker, S.L.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.
Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT805
to be published,
Experimental method
X-RAY DIFFRACTION (1.25 Å)
Structure validation

217705

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