6E2H
Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30
Summary for 6E2H
Entry DOI | 10.2210/pdb6e2h/pdb |
Descriptor | Set1/Ash2 histone methyltransferase complex subunit ASH2, Protein dpy-30 homolog (3 entities in total) |
Functional Keywords | histone, epigenetics, set1, mll, lysine methylation, nucleosome, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 46611.62 |
Authors | Joshi, M.,Brunzelle, J.S.,Couture, J.F. (deposition date: 2018-07-11, release date: 2018-08-08, Last modification date: 2023-10-11) |
Primary citation | Haddad, J.F.,Yang, Y.,Takahashi, Y.H.,Joshi, M.,Chaudhary, N.,Woodfin, A.R.,Benyoucef, A.,Yeung, S.,Brunzelle, J.S.,Skiniotis, G.,Brand, M.,Shilatifard, A.,Couture, J.F. Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation. Structure, 26:1594-, 2018 Cited by PubMed: 30270175DOI: 10.1016/j.str.2018.08.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.236 Å) |
Structure validation
Download full validation report