6E2H

Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30

6E2H の概要

• エントリーDOI: 10.2210/pdb6e2h/pdb
• 分子名称: Set1/Ash2 histone methyltransferase complex subunit ASH2, Protein dpy-30 homolog (3 entities in total)
• 機能のキーワード: histone, epigenetics, set1, mll, lysine methylation, nucleosome, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 46611.62

構造登録者

Joshi, M.,Brunzelle, J.S.,Couture, J.F. (登録日: 2018-07-11, 公開日: 2018-08-08, 最終更新日: 2023-10-11)

• 主引用文献: Haddad, J.F.,Yang, Y.,Takahashi, Y.H.,Joshi, M.,Chaudhary, N.,Woodfin, A.R.,Benyoucef, A.,Yeung, S.,Brunzelle, J.S.,Skiniotis, G.,Brand, M.,Shilatifard, A.,Couture, J.F.; Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation.; Structure, 26:1594-, 2018; PubMed: 30270175; DOI: 10.1016/j.str.2018.08.004

実験手法

X-RAY DIFFRACTION (2.236 Å)