6DUI

Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT801

6DUI の概要

• エントリーDOI: 10.2210/pdb6dui/pdb
• 関連するPDBエントリー: 5UPG 5VWM 6C9C 6CAX
• 分子名称: UDP-3-O-acyl-N-acetylglucosamine deacetylase, (2R)-4-{4-[4-(benzyloxy)phenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2S)-4-{4-[4-(benzyloxy)phenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, ... (7 entities in total)
• 機能のキーワード: ssgcid, lpxc, lipid a biosynthesis, structural genomics, seattle structural genomics center for infectious disease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Pseudomonas aeruginosa (strain LESB58)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34728.20

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2018-06-20, 公開日: 2019-06-26, 最終更新日: 2023-10-11)

• 主引用文献: Phan, J.N.,Delker, S.L.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT801; to be published,

実験手法

X-RAY DIFFRACTION (1.55 Å)