6DJW
Crystal Structure of pParkin (REP and RING2 deleted)-pUb-UbcH7 complex
Summary for 6DJW
Entry DOI | 10.2210/pdb6djw/pdb |
Descriptor | RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... (4 entities in total) |
Functional Keywords | ubiquitin, e3 ligase, e2 conjugating enzyme, phosphorylation, mitophagy, parkinson disease, transferase |
Biological source | Bactrocera dorsalis (Oriental fruit fly) More |
Total number of polymer chains | 3 |
Total formula weight | 66676.13 |
Authors | Sauve, V.,Sung, G.,Trempe, J.F.,Gehring, K. (deposition date: 2018-05-26, release date: 2018-07-04, Last modification date: 2023-10-11) |
Primary citation | Sauve, V.,Sung, G.,Soya, N.,Kozlov, G.,Blaimschein, N.,Miotto, L.S.,Trempe, J.F.,Lukacs, G.L.,Gehring, K. Mechanism of parkin activation by phosphorylation. Nat. Struct. Mol. Biol., 25:623-630, 2018 Cited by PubMed: 29967542DOI: 10.1038/s41594-018-0088-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.801 Å) |
Structure validation
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