6DBC

Second bromodomain of Human BRD2 with a Tetrahydroquinoline analogue

6DBC の概要

• エントリーDOI: 10.2210/pdb6dbc/pdb
• 分子名称: Bromodomain-containing protein 2, 1,2-ETHANEDIOL, 1-[(2S,4R)-4-[(2-chlorophenyl)amino]-2-methyl-6-(1H-pyrazol-3-yl)-3,4-dihydroquinolin-1(2H)-yl]ethan-1-one, ... (4 entities in total)
• 機能のキーワード: bet, brd2, bromodomain, inhibitor, complex, transcription, transcription-inhibitor complex, transcription/inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14339.82

構造登録者

White, S.W.,Yun, M. (登録日: 2018-05-03, 公開日: 2019-11-13, 最終更新日: 2023-10-04)

• 主引用文献: White, S.W.,Yun, M.; Second bromodomain of Human BRD2 with a Tetrahydroquinoline analogue; To Be Published,

実験手法

X-RAY DIFFRACTION (1.05 Å)