6D65

Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein off7

Summary for 6D65

Entry DOI	10.2210/pdb6d65/pdb
Descriptor	Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Designed AR protein off7, GLYCEROL, ... (6 entities in total)
Functional Keywords	dual specificity phosphatase, dusp, c258s, hydrolase, mbp, darpin
Biological source	Escherichia coli (strain K12) More
Total number of polymer chains	4
Total formula weight	154553.60
Authors	Gumpena, R.,Lountos, G.T.,Waugh, D.S. (deposition date: 2018-04-20, release date: 2018-09-19, Last modification date: 2023-10-04)
Primary citation	Gumpena, R.,Lountos, G.T.,Waugh, D.S. MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74:549-557, 2018 Cited by PubMed: 30198887 DOI: 10.1107/S2053230X18009901 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.348 Å)

Structure validation