6D06
Human ADAR2d E488Y mutant complexed with dsRNA containing an abasic site opposite the edited base
Summary for 6D06
Entry DOI | 10.2210/pdb6d06/pdb |
Descriptor | Double-stranded RNA-specific editase 1, RNA (5'-R(*GP*CP*UP*CP*GP*CP*GP*AP*UP*GP*CP*UP*(8AZ)P*GP*AP*GP*GP*GP*CP*UP*CP*UP*G)-3'), RNA (5'-R(*CP*AP*GP*AP*GP*CP*CP*CP*CP*CP*NP*AP*GP*CP*AP*UP*CP*GP*CP*GP*AP*GP*C)-3'), ... (6 entities in total) |
Functional Keywords | adenosine deaminase, rna editing, hydrolase, hydrolase-rna complex, hydrolase/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 106171.59 |
Authors | Matthews, M.M.,Fisher, A.J.,Beal, P.A. (deposition date: 2018-04-10, release date: 2019-02-20, Last modification date: 2023-10-04) |
Primary citation | Monteleone, L.R.,Matthews, M.M.,Palumbo, C.M.,Thomas, J.M.,Zheng, Y.,Chiang, Y.,Fisher, A.J.,Beal, P.A. A Bump-Hole Approach for Directed RNA Editing. Cell Chem Biol, 26:269-, 2019 Cited by PubMed: 30581135DOI: 10.1016/j.chembiol.2018.10.025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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