6CXM

Crystal structure of a dihydrofolate reductase from Mycobacterium smegmatis in complex with NADP and P218

6CXM の概要

• エントリーDOI: 10.2210/pdb6cxm/pdb
• 関連するPDBエントリー: 5U26
• 分子名称: Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, ... (4 entities in total)
• 機能のキーワード: niaid, national institute of allergy and infectious disease, structural genomics, mycobacterium tuberculosis, mtb, inhibitor, seattle structural genomics center for infectious disease, ssgcid, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 39153.48

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2018-04-03, 公開日: 2018-04-11, 最終更新日: 2023-10-04)

• 主引用文献: Edwards, T.E.,Abendroth, J.,Lorimer, D.D.,Horanyi, P.S.,Seattle Structural Genomics Center for Infectious Disease; Crystal structure of a dihydrofolate reductase from Mycobacterium smegmatis in complex with NADP and P218; To Be Published,

実験手法

X-RAY DIFFRACTION (2.65 Å)