5U26
Crystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound to NADP and p218 Inhibitor
Summary for 5U26
Entry DOI | 10.2210/pdb5u26/pdb |
Descriptor | Dihydrofolate reductase, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total) |
Functional Keywords | dhfr, folate, structural genomics, seattle structural genomics center for infectious disease, ssgcid, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 21190.37 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2016-11-29, release date: 2016-12-21, Last modification date: 2023-10-04) |
Primary citation | Mayclin, S.J.,Fairman, J.W.,Lorimer, D.D.,Edwards, T.E. Crystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound to NADP and p218 Inhibitor TO BE PUBLISHED, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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