6CXM
Crystal structure of a dihydrofolate reductase from Mycobacterium smegmatis in complex with NADP and P218
Summary for 6CXM
Entry DOI | 10.2210/pdb6cxm/pdb |
Related | 5U26 |
Descriptor | Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, ... (4 entities in total) |
Functional Keywords | niaid, national institute of allergy and infectious disease, structural genomics, mycobacterium tuberculosis, mtb, inhibitor, seattle structural genomics center for infectious disease, ssgcid, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor |
Biological source | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) |
Total number of polymer chains | 2 |
Total formula weight | 39153.48 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-04-03, release date: 2018-04-11, Last modification date: 2023-10-04) |
Primary citation | Edwards, T.E.,Abendroth, J.,Lorimer, D.D.,Horanyi, P.S.,Seattle Structural Genomics Center for Infectious Disease Crystal structure of a dihydrofolate reductase from Mycobacterium smegmatis in complex with NADP and P218 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
Download full validation report