6CSP

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with cyclohexenylhydroxamate

Summary for 6CSP

Entry DOI	10.2210/pdb6csp/pdb
Descriptor	Hdac6 protein, ZINC ION, POTASSIUM ION, ... (8 entities in total)
Functional Keywords	zinc hydrolase, tubulin deacetylase, hydrolase
Biological source	Danio rerio (Zebrafish)
Total number of polymer chains	2
Total formula weight	82753.94
Authors	Porter, N.J.,Christianson, D.W. (deposition date: 2018-03-21, release date: 2018-05-30, Last modification date: 2024-03-13)
Primary citation	Porter, N.J.,Wagner, F.F.,Christianson, D.W. Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6. Biochemistry, 57:3916-3924, 2018 Cited by PubMed: 29775292 DOI: 10.1021/acs.biochem.8b00367 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.237 Å)

Structure validation