Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 801 |
| Chain | Residue |
| A | ASP612 |
| A | HIS614 |
| A | ASP705 |
| A | FBM807 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue K A 802 |
| Chain | Residue |
| A | ASP610 |
| A | ASP612 |
| A | HIS614 |
| A | SER633 |
| A | LEU634 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue K A 803 |
| Chain | Residue |
| A | PHE623 |
| A | ASP626 |
| A | VAL629 |
| A | TYR662 |
| A | HOH1044 |
| A | HOH1067 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 804 |
| Chain | Residue |
| A | HIS614 |
| B | LYS658 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 805 |
| Chain | Residue |
| A | LYS658 |
| B | HIS614 |
| B | HOH1126 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 806 |
| Chain | Residue |
| A | GLY657 |
| A | HOH1252 |
| A | HOH1297 |
| A | HOH1308 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue FBM A 807 |
| Chain | Residue |
| A | HIS573 |
| A | HIS574 |
| A | GLY582 |
| A | PHE583 |
| A | ASP612 |
| A | HIS614 |
| A | PHE643 |
| A | ASP705 |
| A | TYR745 |
| A | ZN801 |
| A | HOH1173 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 808 |
| Chain | Residue |
| A | LEU557 |
| A | ARG736 |
| A | EDO809 |
| A | HOH912 |
| B | LEU557 |
| B | THR558 |
| B | ARG736 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 809 |
| Chain | Residue |
| A | LEU557 |
| A | ARG736 |
| A | EDO808 |
| A | HOH903 |
| B | LEU557 |
| B | ARG736 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 810 |
| Chain | Residue |
| A | LYS512 |
| A | HIS516 |
| A | HOH909 |
| A | HOH926 |
| B | HOH912 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 811 |
| Chain | Residue |
| A | EDO815 |
| B | LYS658 |
| B | HOH987 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 812 |
| Chain | Residue |
| A | ALA707 |
| A | GLY709 |
| A | ASP710 |
| A | GLY714 |
| A | PHE715 |
| A | HOH915 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 813 |
| Chain | Residue |
| A | TYR448 |
| A | ASP449 |
| A | ARG488 |
| A | ALA491 |
| A | HOH927 |
| A | HOH962 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 814 |
| Chain | Residue |
| A | PRO719 |
| A | GLU720 |
| A | GLU752 |
| A | MET756 |
| A | HOH908 |
| A | HOH963 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 815 |
| Chain | Residue |
| A | HIS463 |
| A | SER531 |
| A | ILE532 |
| A | PHE583 |
| A | EDO811 |
| A | HOH1172 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 816 |
| Chain | Residue |
| A | ARG481 |
| A | SER484 |
| A | HOH913 |
| A | HOH1190 |
| A | HOH1217 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 817 |
| Chain | Residue |
| A | ILE510 |
| A | GLU528 |
| A | TYR529 |
| A | HOH919 |
| A | HOH929 |
| A | HOH1169 |
| B | EDO808 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 801 |
| Chain | Residue |
| B | ASP612 |
| B | HIS614 |
| B | ASP705 |
| B | FBM805 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue K B 802 |
| Chain | Residue |
| B | SER633 |
| B | LEU634 |
| B | ASP610 |
| B | ASP612 |
| B | HIS614 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue K B 803 |
| Chain | Residue |
| B | PHE623 |
| B | ASP626 |
| B | VAL629 |
| B | TYR662 |
| B | HOH1051 |
| B | HOH1088 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 804 |
| Chain | Residue |
| B | HIS487 |
| B | ARG488 |
| B | GLU647 |
| B | EDO810 |
| site_id | AE4 |
| Number of Residues | 11 |
| Details | binding site for residue FBM B 805 |
| Chain | Residue |
| B | HIS573 |
| B | HIS574 |
| B | GLY582 |
| B | PHE583 |
| B | ASP612 |
| B | HIS614 |
| B | PHE643 |
| B | ASP705 |
| B | TYR745 |
| B | ZN801 |
| B | HOH1206 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 806 |
| Chain | Residue |
| B | TRP459 |
| B | ASN523 |
| B | ASP770 |
| B | HIS771 |
| B | HOH919 |
| B | HOH998 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 807 |
| Chain | Residue |
| B | ALA500 |
| B | LEU501 |
| B | CYS502 |
| B | HIS503 |
| B | LYS577 |
| B | HOH1121 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 808 |
| Chain | Residue |
| A | LYS506 |
| A | EDO817 |
| B | GLU515 |
| B | TYR539 |
| B | THR540 |
| site_id | AE8 |
| Number of Residues | 10 |
| Details | binding site for residue EDO B 809 |
| Chain | Residue |
| A | ARG472 |
| A | THR748 |
| B | ARG472 |
| B | ARG476 |
| B | THR748 |
| B | SER751 |
| B | HOH901 |
| B | HOH907 |
| B | HOH1063 |
| B | HOH1086 |
| site_id | AE9 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 810 |
| Chain | Residue |
| B | SER484 |
| B | CYS486 |
| B | GLU647 |
| B | LYS653 |
| B | CL804 |
| B | EDO813 |
| B | HOH914 |
| B | HOH917 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 811 |
| Chain | Residue |
| B | ARG605 |
| B | TYR662 |
| B | PHE693 |
| B | TRP794 |
| B | HOH911 |
| B | HOH921 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 812 |
| Chain | Residue |
| B | HIS684 |
| B | LEU775 |
| B | ILE783 |
| B | ASN784 |
| B | HOH904 |
| site_id | AF3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 813 |
| Chain | Residue |
| B | SER484 |
| B | ARG485 |
| B | CYS486 |
| B | SER646 |
| B | GLU647 |
| B | EDO810 |
| B | HOH994 |
| B | HOH1108 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 814 |
| Chain | Residue |
| B | HIS456 |
| B | MET458 |
| B | SER535 |
| B | ASN536 |
| B | GLU537 |
| B | HOH1027 |
| site_id | AF5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 815 |
| Chain | Residue |
| A | SER513 |
| A | MET517 |
| B | ARG451 |
| B | ARG492 |
| B | LEU493 |
| B | LEU544 |
| B | HOH909 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 816 |
| Chain | Residue |
| B | HIS463 |
| B | ILE532 |
| B | PHE583 |
| B | HOH1079 |
| site_id | AF7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 817 |
| Chain | Residue |
| B | PRO442 |
| B | LEU761 |
| B | LEU762 |
| B | GLY763 |
| B | HOH934 |
| B | HOH1041 |
| B | HOH1171 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 818 |
| Chain | Residue |
| B | ASP652 |
| B | ALA789 |
| B | HOH905 |
| B | HOH923 |
| B | HOH1178 |
