6CS2

SARS Spike Glycoprotein - human ACE2 complex, Stabilized variant, all ACE2-bound particles

Summary for 6CS2

Entry DOI	10.2210/pdb6cs2/pdb
EMDB information	7582
Descriptor	Spike glycoprotein,Fibritin, Angiotensin-converting enzyme 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	membrane fusion, glycoprotein, receptor binding, viral protein, viral protein-hydrolase complex, viral protein/hydrolase
Biological source	Human SARS coronavirus (SARS-CoV) More
Total number of polymer chains	4
Total formula weight	492057.90
Authors	Kirchdoerfer, R.N.,Wang, N.,Pallesen, J.,Turner, H.L.,Cottrell, C.A.,McLellan, J.S.,Ward, A.B. (deposition date: 2018-03-19, release date: 2018-04-11, Last modification date: 2020-07-29)
Primary citation	Kirchdoerfer, R.N.,Wang, N.,Pallesen, J.,Wrapp, D.,Turner, H.L.,Cottrell, C.A.,Corbett, K.S.,Graham, B.S.,McLellan, J.S.,Ward, A.B. Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis. Sci Rep, 8:15701-15701, 2018 Cited by PubMed: 30356097 DOI: 10.1038/s41598-018-34171-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.4 Å)

Structure validation