6CBV
Crystal structure of BRIL bound to an affinity matured synthetic antibody.
Summary for 6CBV
Entry DOI | 10.2210/pdb6cbv/pdb |
Descriptor | Heavy chain, Fab fragment, Light Chain, Fab fragment, BRIL, ... (7 entities in total) |
Functional Keywords | 4-helix bundle, fusion protein, synthetic antibody, fab fragment, fusion protein in complex with fab, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 59759.49 |
Authors | Mukherjee, S.,Skrobek, B.,Kossiakoff, A.A. (deposition date: 2018-02-05, release date: 2019-02-06, Last modification date: 2023-10-04) |
Primary citation | Mukherjee, S.,Erramilli, S.K.,Ammirati, M.,Alvarez, F.J.D.,Fennell, K.F.,Purdy, M.D.,Skrobek, B.M.,Radziwon, K.,Coukos, J.,Kang, Y.,Dutka, P.,Gao, X.,Qiu, X.,Yeager, M.,Eric Xu, H.,Han, S.,Kossiakoff, A.A. Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. Nat Commun, 11:1598-1598, 2020 Cited by PubMed: 32221310DOI: 10.1038/s41467-020-15363-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.872 Å) |
Structure validation
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