6CBV
Crystal structure of BRIL bound to an affinity matured synthetic antibody.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Heavy chain, Fab fragment | polymer | 229 | 24321.1 | 1 | Homo sapiens | ||
| 2 | B (L) | Light Chain, Fab fragment | polymer | 214 | 23353.9 | 1 | Homo sapiens | ||
| 3 | C (B) | BRIL | polymer | 106 | 11785.2 | 1 | UniProt (P0ABE7) Pfam (PF07361) | Escherichia coli | Cytochrome b-562 |
| 4 | D, G (H, L) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | E, H (H, L) | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 6 | F (L) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | I, J, K (H, L, B) | water | water | 18.0 | 320 | Chemie (HOH) |
Sequence modifications
B: 1 - 106 (UniProt: P0ABE7)
| PDB | External Database | Details |
|---|---|---|
| Trp 7 | Met 29 | engineered mutation |
| Ile 102 | His 124 | engineered mutation |
| Leu 106 | Arg 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 59460.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 299.2 | |
| All* | Total formula weight | 59759.5 |
