6CBV

Crystal structure of BRIL bound to an affinity matured synthetic antibody.

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005506	molecular_function	iron ion binding
B	0009055	molecular_function	electron transfer activity
B	0020037	molecular_function	heme binding
B	0022900	biological_process	electron transport chain
B	0042597	cellular_component	periplasmic space
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue GOL H 301

Chain	Residue
B	LYS77
H	HOH443
H	HOH494
H	HOH519
H	SER55
H	SER58
H	SER60
H	TYR104
H	SER186
H	SER187
H	HOH402
H	HOH415

---

site_id	AC2
Number of Residues	7
Details	binding site for residue FMT H 302

Chain	Residue
B	LYS77
B	ASN80
H	TYR53
H	THR61
H	SER62
H	HOH420
L	TYR94

---

site_id	AC3
Number of Residues	5
Details	binding site for residue NA L 301

Chain	Residue
L	LEU183
L	SER184
L	ASP187
L	HOH510
L	HOH527

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL L 302

Chain	Residue
L	GLN38
L	GLY58
L	PRO60
L	HOH444

---

site_id	AC5
Number of Residues	9
Details	binding site for residue FMT L 303

Chain	Residue
H	ASN31
H	PHE136
H	LYS157
H	ASP158
H	HOH441
L	GLN126
L	SER129
L	THR131
L	HOH403

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR194-HIS200
H	TYR208-HIS214

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	13
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"description":"axial binding residue"}

Chain

Residue

Details

---