6C4J

Ligand bound full length hUGDH with A104L substitution

Summary for 6C4J

Entry DOI	10.2210/pdb6c4j/pdb
Descriptor	UDP-glucose 6-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-GLUCOSE, ... (7 entities in total)
Functional Keywords	hugdh, human udp-glucose dehydrogenase, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	12
Total formula weight	678074.92
Authors	Beattie, N.R.,Pioso, B.J.,Wood, Z.A.,Sidlo, A.M. (deposition date: 2018-01-12, release date: 2018-05-16, Last modification date: 2024-03-13)
Primary citation	Beattie, N.R.,Pioso, B.J.,Sidlo, A.M.,Keul, N.D.,Wood, Z.A. Hysteresis and Allostery in Human UDP-Glucose Dehydrogenase Require a Flexible Protein Core. Biochemistry, 57:6848-6859, 2018 Cited by PubMed: 30457329 DOI: 10.1021/acs.biochem.8b00497 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.53 Å)

Structure validation