6BQT
Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and T360
Summary for 6BQT
Entry DOI | 10.2210/pdb6bqt/pdb |
Related | 6BCR 6BCY |
Descriptor | 14-3-3 protein theta, Insulin receptor substrate protein of 53 kDa, peptide (IRSp53), 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (10 entities in total) |
Functional Keywords | phosphate binding protein, protein complex, cytoskeleton regulation, cell motility, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 240310.84 |
Authors | Kast, D.J.,Dominguez, R. (deposition date: 2017-11-28, release date: 2018-12-05, Last modification date: 2023-10-04) |
Primary citation | Kast, D.J.,Dominguez, R. Mechanism of IRSp53 inhibition by 14-3-3. Nat Commun, 10:483-483, 2019 Cited by PubMed: 30696821DOI: 10.1038/s41467-019-08317-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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