6BJZ
Crystal Structure of the Fab fragment of humanized 5c8 antibody containing the fluorescent non-canonical amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine at pH 5.5
Summary for 6BJZ
| Entry DOI | 10.2210/pdb6bjz/pdb |
| Related | 1I9R |
| Descriptor | 5c8 Fab Heavy chain, 5c8 Fab Light chain (3 entities in total) |
| Functional Keywords | immunoglobulin, non canonical aminoacid, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 2 |
| Total formula weight | 48092.46 |
| Authors | Henderson, J.N.,Simmons, C.R.,Mills, J.H. (deposition date: 2017-11-07, release date: 2018-11-14, Last modification date: 2023-11-15) |
| Primary citation | Henderson, J.N.,Simmons, C.R.,Fahmi, N.E.,Jeffs, J.W.,Borges, C.R.,Mills, J.H. Structural Insights into How Protein Environments Tune the Spectroscopic Properties of a Noncanonical Amino Acid Fluorophore. Biochemistry, 59:3401-3410, 2020 Cited by PubMed: 32845612DOI: 10.1021/acs.biochem.0c00474 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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