6BEF

Crystal structure of VACV D13 in complex with 3-formyl rifamycin SV

Summary for 6BEF

• Entry DOI: 10.2210/pdb6bef/pdb
• Related: 6BEB 6BEC 6BED 6BEE 6BEG 6BEH 6BEI
• Descriptor: Scaffold protein D13, (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-8-formyl-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptam ethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate, FORMIC ACID, ... (5 entities in total)
• Functional Keywords: poxvirus, assembly, scaffolding protein, rifampicin resistance protein, immature virion, viral protein
• Biological source: Vaccinia virus WR (VACV)
• Total number of polymer chains: 3
• Total formula weight: 187696.36

Authors

Garriga, D.,Accurso, C.,Coulibaly, F. (deposition date: 2017-10-25, release date: 2018-07-18, Last modification date: 2023-10-04)

• Primary citation: Garriga, D.,Headey, S.,Accurso, C.,Gunzburg, M.,Scanlon, M.,Coulibaly, F.; Structural basis for the inhibition of poxvirus assembly by the antibiotic rifampicin.; Proc. Natl. Acad. Sci. U.S.A., 115:8424-8429, 2018; PubMed: 30068608; DOI: 10.1073/pnas.1810398115

Experimental method

X-RAY DIFFRACTION (3.21 Å)