6B5E

Mycobacterium tuberculosis RmlA in complex with dTDP-glucose

Summary for 6B5E

Entry DOI	10.2210/pdb6b5e/pdb
Descriptor	Glucose-1-phosphate thymidylyltransferase, 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE, MAGNESIUM ION, ... (8 entities in total)
Functional Keywords	nucleotidyltransferase, transferase, product, sugar-modifying
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	8
Total formula weight	269154.98
Authors	Brown, H.A.,Holden, H.M. (deposition date: 2017-09-29, release date: 2018-02-21, Last modification date: 2023-10-04)
Primary citation	Brown, H.A.,Thoden, J.B.,Tipton, P.A.,Holden, H.M. The structure of glucose-1-phosphate thymidylyltransferase from Mycobacterium tuberculosis reveals the location of an essential magnesium ion in the RmlA-type enzymes. Protein Sci., 27:441-450, 2018 Cited by PubMed: 29076563 DOI: 10.1002/pro.3333 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation