6B5E
Mycobacterium tuberculosis RmlA in complex with dTDP-glucose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Glucose-1-phosphate thymidylyltransferase | polymer | 296 | 32592.0 | 8 | UniProt (P9WH13) Pfam (PF00483) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | dTDP-glucose pyrophosphorylase,dTDP-glucose synthase |
| 2 | AA, CA, DA, FA, I... (E, F, G, A, H...) | 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE | non-polymer | 564.3 | 10 | Chemie (DAU) PubChem (439324) PubChem (439651) PubChem (443210) PubChem (6857547) PubChem (6857548) PubChem (6857679) PubChem (10144419) PubChem (10166613) PubChem (10231440) PubChem (10231441) PubChem (10303237) PubChem (10303238) PubChem (11169012) PubChem (20776691) PubChem (20776692) PubChem (20776695) PubChem (20776696) PubChem (20776697) PubChem (20776694) PubChem (46936783) PubChem (59680750) PubChem (684) PubChem (6857546) PubChem (15385493) PubChem (87617873) PubChem (87628065) PubChem (89290045) PubChem (89291379) PubChem (89348944) PubChem (90188772) PubChem (101488590) PubChem (101847812) | |||
| 3 | BA, EA, GA, J, JA... (E, F, G, A, H...) | MAGNESIUM ION | non-polymer | 24.3 | 9 | Chemie (MG) PubChem (888) | |||
| 4 | HA, K, KA, Q, U... (G, A, H, B, C...) | THYMIDINE-5'-DIPHOSPHATE | non-polymer | 402.2 | 6 | Chemie (TYD) | |||
| 5 | L (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | M (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | R, V (B, C) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 8 | LA, MA, NA, OA, PA... (A, B, C, D, E...) | water | water | 18.0 | 1477 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 288 (UniProt: P9WH13)
| PDB | External Database | Details |
|---|---|---|
| Leu 289 | - | expression tag |
| Glu 290 | - | expression tag |
| His 291 | - | expression tag |
| His 292 | - | expression tag |
| His 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
| His 296 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 260736.3 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 8418.7 | |
| All* | Total formula weight | 269155.0 |
