6ZBZ
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
Summary for 6ZBZ
Entry DOI | 10.2210/pdb6zbz/pdb |
Descriptor | Dishevelled, dsh homolog 3 (Drosophila), isoform CRA_b, 2-[(3,4-dimethylphenyl)sulfonylamino]-5-fluoranyl-benzoic acid, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | pdz, dvl, inhibitors, wnt, signalling, peptide binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 42278.28 |
Authors | Roske, Y.,Heinemann, U.,Oschkinat, H. (deposition date: 2020-06-09, release date: 2021-06-23, Last modification date: 2024-01-24) |
Primary citation | Roske, Y.,Heinemann, U.,Oschkinat, H.,Kamdem, N.,Kovalskyy, D.,Platonov, M.O.,Balinskyi, O.M.,Kreuchwig, A.,Saupe, J.,Fang, L.,Diehl, A.,Schmieder, P.,Krause, G.,Rademann, J.,Birchmeier, W. Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021 Cited by DOI: 10.5194/mr-2-355-2021PDB entries with the same primary citation |
Experimental method |
Structure validation
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