6X9H
Molecular mechanism and structural basis of small-molecule modulation of acid-sensing ion channel 1 (ASIC1)
Summary for 6X9H
Entry DOI | 10.2210/pdb6x9h/pdb |
Descriptor | Acid-sensing ion channel 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-[4-(3,4-dimethoxyphenoxy)phenyl]-1H-benzimidazole-6-carboximidamide, ... (4 entities in total) |
Functional Keywords | asic1, modulation, membrane protein, transport protein |
Biological source | Gallus gallus (Chicken) |
Total number of polymer chains | 3 |
Total formula weight | 152314.13 |
Authors | Liu, Y.,Ma, J.,DesJarlais, R.L.,Hagan, R.,Rech, J.,Lin, D.,Liu, C.,Miller, R.,Schoellerman, J.,Luo, J.,Letavic, M.,Grasberger, B.,Maher, M. (deposition date: 2020-06-02, release date: 2020-12-30, Last modification date: 2023-10-18) |
Primary citation | Liu, Y.,Ma, J.,DesJarlais, R.L.,Hagan, R.,Rech, J.,Lin, D.,Liu, C.,Miller, R.,Schoellerman, J.,Luo, J.,Letavic, M.,Grasberger, B.,Maher, M. Molecular mechanism and structural basis of small-molecule modulation of the gating of acid-sensing ion channel 1. Commun Biol, 4:174-174, 2021 Cited by PubMed: 33564124DOI: 10.1038/s42003-021-01678-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.01 Å) |
Structure validation
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