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6X9H

Molecular mechanism and structural basis of small-molecule modulation of acid-sensing ion channel 1 (ASIC1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Acid-sensing ion channel 1polymer43850154.13UniProt (Q1XA76)
Pfam (PF00858)
Gallus gallus (Chicken)ASIC1,Amiloride-sensitive cation channel 2,neuronal
2D, G, I
(A, B, C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
3E, H, J
(A, B, C)
2-[4-(3,4-dimethoxyphenoxy)phenyl]-1H-benzimidazole-6-carboximidamidenon-polymer388.43Chemie (UZG)
4F
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight150462.3
Non-Polymers*Number of molecules7
Total formula weight1851.9
All*Total formula weight152314.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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