6WT7
Structure of a metazoan TIR-STING receptor from C. gigas in complex with 2',3'-cGAMP
Summary for 6WT7
Entry DOI | 10.2210/pdb6wt7/pdb |
Descriptor | Metazoan TIR-STING fusion, cGAMP (2 entities in total) |
Functional Keywords | tir domain, cyclic dinucleotide receptor, immune effector, immune system |
Biological source | Crassostrea gigas |
Total number of polymer chains | 1 |
Total formula weight | 47737.70 |
Authors | Morehouse, B.R.,Govande, A.A.,Millman, A.,Keszei, A.F.A.,Lowey, B.,Ofir, G.,Shao, S.,Sorek, R.,Kranzusch, P.J. (deposition date: 2020-05-01, release date: 2020-09-09, Last modification date: 2024-03-06) |
Primary citation | Morehouse, B.R.,Govande, A.A.,Millman, A.,Keszei, A.F.A.,Lowey, B.,Ofir, G.,Shao, S.,Sorek, R.,Kranzusch, P.J. STING cyclic dinucleotide sensing originated in bacteria. Nature, 586:429-433, 2020 Cited by PubMed: 32877915DOI: 10.1038/s41586-020-2719-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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