6U1N
GPCR-Beta arrestin structure in lipid bilayer
Summary for 6U1N
Entry DOI | 10.2210/pdb6u1n/pdb |
EMDB information | 20612 |
Descriptor | Muscarinic acetylcholine receptor M2, Vasopressin V2 receptor chimera, Beta-arrestin-1, Fab30 heavy chain, ... (5 entities in total) |
Functional Keywords | arrestin, gpcr, complex, signaling, signaling protein-immune system complex, signaling protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 151018.72 |
Authors | Staus, D.P.,Hu, H.,Robertson, M.J.,Kleinhenz, A.L.W.,Wingler, L.M.,Capel, W.D.,Latorraca, N.R.,Lefkowitz, R.J.,Skiniotis, G. (deposition date: 2019-08-16, release date: 2020-02-26, Last modification date: 2020-03-25) |
Primary citation | Staus, D.P.,Hu, H.,Robertson, M.J.,Kleinhenz, A.L.W.,Wingler, L.M.,Capel, W.D.,Latorraca, N.R.,Lefkowitz, R.J.,Skiniotis, G. Structure of the M2 muscarinic receptor-beta-arrestin complex in a lipid nanodisc. Nature, 579:297-302, 2020 Cited by PubMed: 31945772DOI: 10.1038/s41586-020-1954-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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