6RMG
Structure of PTCH1 bound to a modified Hedgehog ligand ShhN-C24II
Summary for 6RMG
Entry DOI | 10.2210/pdb6rmg/pdb |
EMDB information | 4936 |
Descriptor | Protein patched homolog 1,GFP-like fluorescent chromoprotein FP506, related, Sonic hedgehog protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | patched, ptch1, hedgehog, shhn, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 203194.08 |
Authors | Korkhov, V.M.,Qi, C. (deposition date: 2019-05-06, release date: 2019-10-09, Last modification date: 2020-07-29) |
Primary citation | Qi, C.,Di Minin, G.,Vercellino, I.,Wutz, A.,Korkhov, V.M. Structural basis of sterol recognition by human hedgehog receptor PTCH1. Sci Adv, 5:eaaw6490-eaaw6490, 2019 Cited by PubMed: 31555730DOI: 10.1126/sciadv.aaw6490 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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