6PW8
Hydrocarbon-Stapled Paxillin Peptide Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK)
Summary for 6PW8
Entry DOI | 10.2210/pdb6pw8/pdb |
Descriptor | Focal adhesion kinase 1, SP3, ZINC ION, ... (5 entities in total) |
Functional Keywords | inhibitor, stapled peptide, tyrosine kinase, protein binding-inhibitor complex, protein binding/inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 15780.30 |
Authors | Thifault, D.G.,Fromme, P.,Martin-Garcia, J.M. (deposition date: 2019-07-22, release date: 2020-07-22, Last modification date: 2023-11-15) |
Primary citation | Thifault, D.G.,Fromme, P.,Martin-Garcia, J.M. Stapled Peptide Ligand Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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