6OTC
Synthetic Fab bound to Marburg virus VP35 interferon inhibitory domain
Summary for 6OTC
Entry DOI | 10.2210/pdb6otc/pdb |
Descriptor | Polymerase cofactor VP35, sFab H3 heavy chain, sFab H3 light chain, ... (6 entities in total) |
Functional Keywords | marburg virus, fab, viral protein-immune system complex, viral protein/immune system |
Biological source | Lake Victoria marburgvirus (strain Popp-67) (MARV) More |
Total number of polymer chains | 3 |
Total formula weight | 65360.52 |
Authors | Amatya, P.,Chen, G.,Borek, D.,Sidhu, S.S.,Leung, D.W. (deposition date: 2019-05-02, release date: 2019-06-05, Last modification date: 2023-10-11) |
Primary citation | Amatya, P.,Wagner, N.,Chen, G.,Luthra, P.,Shi, L.,Borek, D.,Pavlenco, A.,Rohrs, H.,Basler, C.F.,Sidhu, S.S.,Gross, M.L.,Leung, D.W. Inhibition of Marburg Virus RNA Synthesis by a Synthetic Anti-VP35 Antibody. Acs Infect Dis., 5:1385-1396, 2019 Cited by PubMed: 31120240DOI: 10.1021/acsinfecdis.9b00091 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report