6KUX
Crystal structures of the alpha2A adrenergic receptor in complex with an antagonist RSC.
Summary for 6KUX
Entry DOI | 10.2210/pdb6kux/pdb |
Descriptor | alpha2A adrenergic receptor, (8~{a}~{R},12~{a}~{S},13~{a}~{S})-12-ethylsulfonyl-3-methoxy-5,6,8,8~{a},9,10,11,12~{a},13,13~{a}-decahydroisoquinolino[2,1-g][1,6]naphthyridine, DI(HYDROXYETHYL)ETHER, ... (5 entities in total) |
Functional Keywords | alpha2a adrenergic receptor, antagonist, gpcr, signaling protein |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 45857.57 |
Authors | Qu, L.,Zhou, Q.T.,Wu, D.,Zhao, S.W. (deposition date: 2019-09-02, release date: 2019-12-04, Last modification date: 2023-11-22) |
Primary citation | Qu, L.,Zhou, Q.T.,Wu, D.,Zhao, S.W. Crystal structures of the alpha2A adrenergic receptor in complex with an antagonist RSC. To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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