6GJK
A degradation product of PD 404182 (P2742) bound to Histone Deacetylase-like Amidohydrolase
Summary for 6GJK
Entry DOI | 10.2210/pdb6gjk/pdb |
Descriptor | Histone deacetylase-like amidohydrolase, ZINC ION, POTASSIUM ION, ... (9 entities in total) |
Functional Keywords | hdah, hdac, p2742, pd 404182, histone deacetylase-like amidohydrolase, histone deacetylase, covalent modification, hydrolase |
Biological source | Alcaligenaceae bacterium FB188 |
Total number of polymer chains | 2 |
Total formula weight | 82928.75 |
Authors | Kraemer, A.,Meyer-Almes, F.J. (deposition date: 2018-05-16, release date: 2019-01-16, Last modification date: 2024-01-17) |
Primary citation | Muth, M.,Jansch, N.,Kopranovic, A.,Kramer, A.,Wossner, N.,Jung, M.,Kirschhofer, F.,Meyer-Almes, F.J. Covalent inhibition of histone deacetylase 8 by 3,4-dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine. Biochim Biophys Acta Gen Subj, 1863:577-585, 2019 Cited by PubMed: 30611847DOI: 10.1016/j.bbagen.2019.01.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.47 Å) |
Structure validation
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