6EA5

Structure of BDBV GPcl in complex with the pan-ebolavirus mAb ADI-15878

Summary for 6EA5

• Entry DOI: 10.2210/pdb6ea5/pdb
• Descriptor: Envelope glycoprotein, Glycoprotein, ADI-15878 Fab Heavy Chain, ... (7 entities in total)
• Functional Keywords: mab, gp, glycoprotein, ebola, ebov, antibody, bdbv, bundibugyo, neutralization, immune, bnab, complex, filovirus, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Bundibugyo ebolavirus; More
• Total number of polymer chains: 12
• Total formula weight: 236573.35

Authors

King, L.B.,West, B.R.,Moyer, C.L.,Fusco, M.L.,Milligan, J.C.,Hui, S.,Saphire, E.O. (deposition date: 2018-08-02, release date: 2018-09-19, Last modification date: 2023-10-11)

• Primary citation: West, B.R.,Moyer, C.L.,King, L.B.,Fusco, M.L.,Milligan, J.C.,Hui, S.,Saphire, E.O.; Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope.; MBio, 9:-, 2018; PubMed: 30206174; DOI: 10.1128/mBio.01674-18

Experimental method

X-RAY DIFFRACTION (4.75 Å)