6E7I
Human ppGalNAcT2 I253A/L310A Mutant with EA2 and UDP
Summary for 6E7I
Entry DOI | 10.2210/pdb6e7i/pdb |
Descriptor | Polypeptide N-acetylgalactosaminyltransferase 2, EA2, URIDINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | glycosyltransferase, glycosylation, bump-hole, galnac, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 62447.64 |
Authors | Bertozzi, C.R.,Schumann, B.,Agbay, A.J. (deposition date: 2018-07-26, release date: 2020-01-29, Last modification date: 2023-10-11) |
Primary citation | Schumann, B.,Malaker, S.A.,Wisnovsky, S.P.,Debets, M.F.,Agbay, A.J.,Fernandez, D.,Wagner, L.J.S.,Lin, L.,Li, Z.,Choi, J.,Fox, D.M.,Peh, J.,Gray, M.A.,Pedram, K.,Kohler, J.J.,Mrksich, M.,Bertozzi, C.R. Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells. Mol.Cell, 78:824-834.e15, 2020 Cited by PubMed: 32325029DOI: 10.1016/j.molcel.2020.03.030 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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