6BNK
Crystal structure of TCR-MHC-like molecule
Summary for 6BNK
Entry DOI | 10.2210/pdb6bnk/pdb |
Descriptor | Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, NKT Valpha14 (MOUSE) - 2C12 TCR - Hybrid mouse variable and human constant domains, ... (8 entities in total) |
Functional Keywords | lipids cancer, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 8 |
Total formula weight | 195881.33 |
Authors | Le Nours, J.,Rossjohn, J. (deposition date: 2017-11-16, release date: 2018-04-04, Last modification date: 2023-10-04) |
Primary citation | Chennamadhavuni, D.,Saavedra-Avila, N.A.,Carreno, L.J.,Guberman-Pfeffer, M.J.,Arora, P.,Yongqing, T.,Koay, H.F.,Godfrey, D.I.,Keshipeddy, S.,Richardson, S.K.,Sundararaj, S.,Lo, J.H.,Wen, X.,Gascon, J.A.,Yuan, W.,Rossjohn, J.,Le Nours, J.,Porcelli, S.A.,Howell, A.R. Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity. Cell Chem Biol, 25:571-, 2018 Cited by PubMed: 29576533DOI: 10.1016/j.chembiol.2018.02.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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