6APD
Crystal structure of RSV F bound by AM22 and the infant antibody ADI-19425
Summary for 6APD
| Entry DOI | 10.2210/pdb6apd/pdb |
| Descriptor | Fusion glycoprotein F0,Envelope glycoprotein, AM22 Fab Heavy Chain,IGH@ protein, AM22 Fab Light Chain,Uncharacterized protein, ... (5 entities in total) |
| Functional Keywords | viral glycoprotein, immunoglobulin, infant, complex, immune system |
| Biological source | Respiratory syncytial virus More |
| Total number of polymer chains | 15 |
| Total formula weight | 474123.09 |
| Authors | Wrapp, D.,McLellan, J.S. (deposition date: 2017-08-17, release date: 2018-03-21, Last modification date: 2020-01-01) |
| Primary citation | Goodwin, E.,Gilman, M.S.A.,Wrapp, D.,Chen, M.,Ngwuta, J.O.,Moin, S.M.,Bai, P.,Sivasubramanian, A.,Connor, R.I.,Wright, P.F.,Graham, B.S.,McLellan, J.S.,Walker, L.M. Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation. Immunity, 48:339-349.e5, 2018 Cited by PubMed: 29396163DOI: 10.1016/j.immuni.2018.01.005 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (4.1 Å) |
Structure validation
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