6APD
Crystal structure of RSV F bound by AM22 and the infant antibody ADI-19425
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| C | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| E | 0002250 | biological_process | adaptive immune response |
| E | 0002376 | biological_process | immune system process |
| E | 0005576 | cellular_component | extracellular region |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0019814 | cellular_component | immunoglobulin complex |
| E | 0046872 | molecular_function | metal ion binding |
| G | 0002250 | biological_process | adaptive immune response |
| G | 0002376 | biological_process | immune system process |
| G | 0005576 | cellular_component | extracellular region |
| G | 0005886 | cellular_component | plasma membrane |
| G | 0019814 | cellular_component | immunoglobulin complex |
| G | 0046872 | molecular_function | metal ion binding |
| I | 0002250 | biological_process | adaptive immune response |
| I | 0002376 | biological_process | immune system process |
| I | 0005576 | cellular_component | extracellular region |
| I | 0005886 | cellular_component | plasma membrane |
| I | 0019814 | cellular_component | immunoglobulin complex |
| I | 0046872 | molecular_function | metal ion binding |
| J | 0002250 | biological_process | adaptive immune response |
| J | 0002376 | biological_process | immune system process |
| J | 0003823 | molecular_function | antigen binding |
| J | 0005576 | cellular_component | extracellular region |
| J | 0005886 | cellular_component | plasma membrane |
| J | 0016020 | cellular_component | membrane |
| J | 0016064 | biological_process | immunoglobulin mediated immune response |
| J | 0019814 | cellular_component | immunoglobulin complex |
| K | 0002250 | biological_process | adaptive immune response |
| K | 0002376 | biological_process | immune system process |
| K | 0003823 | molecular_function | antigen binding |
| K | 0005576 | cellular_component | extracellular region |
| K | 0005886 | cellular_component | plasma membrane |
| K | 0016020 | cellular_component | membrane |
| K | 0016064 | biological_process | immunoglobulin mediated immune response |
| K | 0019814 | cellular_component | immunoglobulin complex |
| N | 0002250 | biological_process | adaptive immune response |
| N | 0002376 | biological_process | immune system process |
| N | 0003823 | molecular_function | antigen binding |
| N | 0005576 | cellular_component | extracellular region |
| N | 0005886 | cellular_component | plasma membrane |
| N | 0016020 | cellular_component | membrane |
| N | 0016064 | biological_process | immunoglobulin mediated immune response |
| N | 0019814 | cellular_component | immunoglobulin complex |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| J | TYR194-HIS200 | |
| E | TYR192-HIS198 | |
| L | TYR192-HIS198 | |
| D | TYR194-HIS200 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin-like protease => ECO:0000269|PubMed:11493675, ECO:0000269|PubMed:12127793 |
| Chain | Residue | Details |
| A | ARG109 | |
| B | ARG109 | |
| C | ARG109 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin-like protease => ECO:0000269|PubMed:11369882, ECO:0000269|PubMed:12127793 |
| Chain | Residue | Details |
| A | ARG136 | |
| B | ARG136 | |
| C | ARG136 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636 |
| Chain | Residue | Details |
| A | ASN27 | |
| B | ASN27 | |
| C | ASN27 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:28469033 |
| Chain | Residue | Details |
| A | ASN70 | |
| B | ASN70 | |
| C | ASN70 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN116 | |
| A | ASN120 | |
| A | ASN126 | |
| B | ASN116 | |
| B | ASN120 | |
| B | ASN126 | |
| C | ASN116 | |
| C | ASN120 | |
| C | ASN126 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:24179220 |
| Chain | Residue | Details |
| A | ASN500 | |
| B | ASN500 | |
| C | ASN500 |
