5YWT

Crystal structure of TREX1 in complex with a duplex DNA with 3' overhang

Summary for 5YWT

• Entry DOI: 10.2210/pdb5ywt/pdb
• Descriptor: Three-prime repair exonuclease 1, DNA (5'-D(*GP*GP*CP*CP*CP*T)-3'), MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: trex1, exonuclease, deddh family, protein-dna complex, dna binding protein-dna complex, dna binding protein
• Biological source: Mus musculus (Mouse); More
• Cellular location: Nucleus: Q91XB0
• Total number of polymer chains: 4
• Total formula weight: 71555.24

Authors

Hsiao, Y.Y. (deposition date: 2017-11-30, release date: 2018-05-23, Last modification date: 2023-11-22)

• Primary citation: Huang, K.W.,Liu, T.C.,Liang, R.Y.,Chu, L.Y.,Cheng, H.L.,Chu, J.W.,Hsiao, Y.Y.; Structural basis for overhang excision and terminal unwinding of DNA duplexes by TREX1; PLoS Biol., 16:e2005653-e2005653, 2018; PubMed: 29734329; DOI: 10.1371/journal.pbio.2005653

Experimental method

X-RAY DIFFRACTION (1.7 Å)