5YHW

Crystal structure of Pig SAMHD1

Summary for 5YHW

• Entry DOI: 10.2210/pdb5yhw/pdb
• Descriptor: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: pig-samhd1, hydrolase
• Biological source: Sus scrofa (Pig)
• Total number of polymer chains: 8
• Total formula weight: 498747.26

Authors

Qin, X.H.,Kong, J. (deposition date: 2017-09-30, release date: 2018-10-17, Last modification date: 2023-11-22)

• Primary citation: Kong, J.,Wang, M.M.,He, S.Y.,Peng, X.,Qin, X.H.; Structural characterization and directed modification of Sus scrofa SAMHD1 reveal the mechanism underlying deoxynucleotide regulation.; Febs J., 286:3844-3857, 2019; PubMed: 31152619; DOI: 10.1111/febs.14943

Experimental method

X-RAY DIFFRACTION (2.7 Å)