5YHW

Crystal structure of Pig SAMHD1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	polymer	524	60773.3	8	UniProt (I3LG77) Pfam (PF01966) In PDB	Sus scrofa (Pig)
2	D, E, A, F, G...	2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	24	Chemie (DGT)
3	D, E, A, F, G...	MAGNESIUM ION	non-polymer		24.3	16	Chemie (MG)
4		water	water		18.0	43	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 110 - 627 (UniProt: I3LG77)

PDB	External Database	Details
His 104	-	expression tag
His 105	-	expression tag
His 106	-	expression tag
His 107	-	expression tag
His 108	-	expression tag
His 109	-	expression tag
Arg 206	His 206	engineered mutation
Asn 207	Asp 207	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	486186.0
Non-Polymers*	Number of molecules	40
	Total formula weight	12561.2
All*	Total formula weight	498747.3

*Water molecules are not included.