5Y8M

Mycobacterium tuberculosis 3-Hydroxyisobutyrate dehydrogenase (MtHIBADH) + NAD + (R)-3-hydroxyisobutyrate (R-HIBA)

Summary for 5Y8M

• Entry DOI: 10.2210/pdb5y8m/pdb
• Descriptor: Probable 3-hydroxyisobutyrate dehydrogenase, GLYCEROL, ACRYLIC ACID, ... (7 entities in total)
• Functional Keywords: 3-hydroxy acid dehydrogenase, enzyme substrate interactions, mechanism of enzyme action, oxidoreductase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Total number of polymer chains: 2
• Total formula weight: 61082.40

Authors

Srikalaivani, R.,Singh, A.,Surolia, A.,Vijayan, M. (deposition date: 2017-08-21, release date: 2018-07-11, Last modification date: 2024-03-27)

• Primary citation: Srikalaivani, R.,Singh, A.,Vijayan, M.,Surolia, A.; Structure, interactions and action ofMycobacterium tuberculosis3-hydroxyisobutyric acid dehydrogenase.; Biochem. J., 475:2457-2471, 2018; PubMed: 29959185; DOI: 10.1042/BCJ20180271

Experimental method

X-RAY DIFFRACTION (2.04 Å)