5Y8M
Mycobacterium tuberculosis 3-Hydroxyisobutyrate dehydrogenase (MtHIBADH) + NAD + (R)-3-hydroxyisobutyrate (R-HIBA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Probable 3-hydroxyisobutyrate dehydrogenase | polymer | 295 | 29837.1 | 2 | UniProt (P9WNY5) Pfam (PF03446) Pfam (PF14833) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | HIBADH |
| 2 | C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | F (A) | ACRYLIC ACID | non-polymer | 72.1 | 1 | Chemie (AKR) | |||
| 4 | G, J (A, B) | (2~{S})-2-methylpentanedioic acid | non-polymer | 146.1 | 2 | Chemie (9ON) | |||
| 5 | H (B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 6 | I (B) | (2R)-3-HYDROXY-2-METHYLPROPANOIC ACID | non-polymer | 104.1 | 1 | Chemie (HIU) | |||
| 7 | K, L (A, B) | water | water | 18.0 | 551 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 294 (UniProt: P9WNY5)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59674.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1408.2 | |
| All* | Total formula weight | 61082.4 |
