5Y7G

Crystal structure of paFAN1 bound to 1nt 5'flap DNA with gap

Summary for 5Y7G

• Entry DOI: 10.2210/pdb5y7g/pdb
• Descriptor: Fanconi-associated nuclease 1 homolog, DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), DNA (5'-D(P*GP*AP*AP*TP*GP*TP*GP*TP*GP*TP*CP*TP*CP*AP*AP*TP*CP*CP*CP*AP*AP*CP*TP*T)-3'), ... (5 entities in total)
• Functional Keywords: nuclease, hydrolase-dna complex, hydrolase/dna
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); More
• Total number of polymer chains: 12
• Total formula weight: 244990.94

Authors

Cho, Y.,Jin, H. (deposition date: 2017-08-17, release date: 2018-03-14, Last modification date: 2023-11-22)

• Primary citation: Jin, H.,Roy, U.,Lee, G.,Scharer, O.D.,Cho, Y.; Structural mechanism of DNA interstrand cross-link unhooking by the bacterial FAN1 nuclease.; J. Biol. Chem., 293:6482-6496, 2018; PubMed: 29514982; DOI: 10.1074/jbc.RA118.002171

Experimental method

X-RAY DIFFRACTION (3.4 Å)